GOAT MILK: A CHALLENGE FOR RESEARCH AND DEVELOPMENT SECTOR FROM ROMANIA
Keywords:
milk, goat caseins, polymorphisms, cheese, authenticity, allergiesAbstract
In the past 20 years the study of goat caseins genetic polymorphisms received a considerable research interest. In particular the researches were focused on CSN1S1 locus which is the most polymorphic, 17 alleles being known so far. These
alleles are associated with four different levels of protein synthesis, affecting significantly goat milk quality and its technological properties. In this context the present review is describing recent literature data at international and national
level, which allow the understanding of goat milk quality variation in relation with its physical-chemical characteristics, milk protein genetic polymorphisms and physiological factors. We also describe the current stage of researches concerning
the use of milk protein polymorphisms in identifying possible adulterations from dairy industry and also studies on milk allergenic potency.
References
Addeo, F., L., Chianese, L., Moio (1990) - Detection of bovine, caprine, ovine and water buffalo’s milk in mixtures by gel electrophoresis of caseins: a review, FIL-IDF Group A7 - Ewes and goats milk;
Balteanu, V.A., A., Vlaic, F.D., Pop, A.R., Rusu, A., Odagiu, V., Cighi, S.,
Creanga (2007) - αS1-casein alleles frequency in Carpathian goat, Buletinul USAMV,Cluj-Napoca, Seria ZB, 63-64, 527;
Balteanu V.A., A., Vlaic, A.R., Rusu, S., Creanga, F.D., Pop, A., Odagiu,
M.L., Pantea, V., Hancu (2007) - Milk proteins polymorphism in Romanian Grey Steppe Cattle studied by isoelectric focusing technique (IEF). Identification of a new allele: αs1 IRV, Buletinul USAMV Cluj-Napoca, Seria Zootehnie si Biotehnologii, 63-64, 304;
Balteanu V.A., A., Vlaic, A.R., Rusu , F.D., Pop, A., Odagiu, S., Creanga
(2007) - Identification of two possible new casein alleles in Romanian buffalo milk: αS1-casein BRV, β-casein CRV, Buletinul USAMV Cluj-Napoca, Seria Zootehnie si Biotehnologii, 63-64, 528;
Balteanu V.A., Vlaic A., A.R., Rusu, S., Creanga, R.F., Pop, V., Cighi (2007) -Milk proteins polymorphism in Romanian cattle breeds, identified by isoelectric focusing technique (IEF), Lucrari Stiintifice seria Zootehnie, Iasi, 50, 173
Balteanu V. A. (2005) - Milk proteins polymorphism in Romanian cattle, buffalo and goat breeds studied by isoelectric focusing technique. Identification of 2 new casein allele: αs1-casein IRV in Romanian Grey Steppe Cattle and αs1-cazeina BRV in Romanian Buffalo, MSc thesis, Faculty of Animal Husbandry and Biotechnologies, Animal Genetics Department, Cluj-Napoca, România.
Cappuccio, I., L. Pariset, P. Ajmone-Marsan, S. Dunner, O. Cortes, G. Erhardt,G. Lühken, K. Gutscher, S. Joost, I.J. Nijman, J.A. Lenstra, P.R. England, S. Zundel,G. Obexer-Ruff, A. Beja-Pereira, A. Valentini, Vlaic A. (Econogene Consortium) 2006 -Allele frequencies and diversity parameters of 27 single nucleotide polymorphisms within and across goat breeds, Molecular Ecology Notes, 6, 992;
Caroli A., F.,Chiatti, S., Chessa, D., Rignanese, P., Bolla, G., Pagnacco
(2006) - Focusing on the goat casein complex, J. of Dairy Science 89, 3178;
Clark, S., J.W., Sherbon (2000) - Genetic variants of alphas1-cn in goat milk:breed distribution and association with milk composition and coagulation properties of goat milk, Small Ruminant Research, 38, 123;
Chanat, E., P., Martin, M., Ollivier-Bousquet (1999) - αs1-casein is required for the efficient transport of β and k-casein from the endoplasmic-reticulum to the Golgi apparatus of mammary epithelial cells, Journal of Cell Science, 112, 3399;
Delacroix B.A., G., Lamberet (2000) - Sensorial properties and typicity of goat dairy products, 7th International Conference on Goats, France, 559;
Grosclaude, F., G., Ricordeau, P,. Martin, F. Remeuf, L., Vassal, J.,
Bouillon (1994) - Du gene au fromage: Le polymorphisme de la caseine α-s1 caprine, ses effets, son evolution. INRA Prod. Anim. 7, 3;
Grosclaude, F., Mahé, M.F., Brignon, G., di Stasio, L. & Juenet, R. (1987). A Mendelian polymorphism underlying quantitative variation of goat αs1-casein. Genet. Sel.Evol. 19, 399;
Haenlein G.F.W. (2004) - Goat milk in human nutrition, Small Ruminant Research 51, 155;
Jaubert, G. (1997) - Biochemical characteristics and quality of goat milk, Inst.Agronomique Mediterraneen , 71;
Leroux, C., F. Le Provost, E., Petit, L., Bernard, Y., Chilliard (2003) - Real time and cDNA macroarray to study the impact of the genetic polymorphism at the alpha s1-casein locus on the expression of genes in the goat mammary gland during lactation, Reproduction nutrition development 43, 459;
Manfredi, E, J.M., Serradilla, C., Leroux, P., Martin, A., Sanchez (2000) – Genetics for milk production, 7th Intern. Conf. on Goat, France, 2000;
Martin, P., M., Szymanowska, L., Zwierzchowski, C., Leroux (2002) - The impact of genetic polymorphism on the protein composition of ruminant milks, Reproduction nutrition development 42, 433;
Marletta, D., Bordonaro, S., Guastella, A. M., Falagiani, P., Crimi, N.G.,
D'Urso (2004) - Goat milk with different αS2-casein content: analysis of allergenic potency
by REAST-inhibition assay, Small Ruminant Research, 52: 19 – 24;
Park Y.W., M. Juarez, M. Ramos, G.F.W. Haenlein (2007) - Physico-chemical characteristics of goat and sheep milk, Small Rum. Research 68, 88;
Pop, F. D., V.A., Balteanu, A., Vlaic (2007) - Identificare rapida a laptelui de vaca in laptele de bivol si capra, utilizand tehnica de focalizare izoelectrica, Agricultura , XVI, special number, page.105, Ed. Academicpres, Cluj-Napoca;
Pop, F. D., V.A., Balteanu, A., Vlaic (2007) - Polimorfismul proteinelor din lapte la rasele romanesti de caprine determinat prin tehnica focalizarii izoelectrice, Agricultura, XVI, special number, page.106, Ed. Academicpres, Cluj-Napoca;
Ramunno, L., G., Cosenza, A., Rando, A., Pauciullo, R., Illario, D., Gallo, D., Di Bernardino, P., Masina (2005) - Comparative analysis of gene of goat CSN1S1 F and N alleles and characterization of CSN1S1 transcript variants in mammary gland, Gene, 345, 289;
Ramunno, L., E., Longobardi, M., Pappalardo, A., Rando, P., Di Gregorio, G., Cosenza, P., Mariani, N., Pastore and P.. Masina (2001b) - An allele associated with a non detectable amount of alphas 2-casein in goat milk, Anim. Genet. 32:19–26;
Remeuf, F. (1993) - Influence du polymorphisme génétique de la caséine αs1 caprine sur les caractéristiques physico-chimiques et technologiques du lait, Lait 73, 549 ;
Sanchez A., H. Ilahi, E. Manfredi, J. M. Serradilla (2005) - Potential benefit from using the as1-casein genotype information in a selection scheme for dairy goats, J.Anim. Breed. Genet, 122, 21;
Sharma S., P., Kumar, C., Betzel, T.P., Singh (2001) - Structure and function of proteins involved in milk allergies, J. of Chromatography B, 756: 183–187;
Vassal L., A. Delacroix-Buchet, J., Bouillon (1994) - Influence des variants AA,EE et FF de la caseine as1 caprine sur le rendement fromager et les caracteristiques sensorielles de fromages traditionnels: premieres observations, Lait 74, 89-103;
Vlaic, A., V.A., Balteanu, F.D. Pop (2008) - Molecular methods used in
detection of cattle milk in buffalo, ewe and goat in dairy products, Lucrari Stiintifice seria Zootehnie, Iasi, Vol. 51, accepted for publication.
